
Marcelo DeSantis
Technology executive · Angel investor · Podcast host · Former senior digital transformation executive, ThoughtWorks
Conversations
The only moats left
Why data and relationships are the last durable advantages in the age of AI, the one question every investor should ask an AI startup, and the moat nobody is building yet.
Transcript →In their words
When agents handle eighty percent of a company's processes, the only thing left that differs from one company to the next is its corporate DNA. That context is the moat.C·009
Corridor Context
Marcelo DeSantis is a technology executive, angel investor, and podcast host who came to the US from Argentina and built a career across consumer goods, automotive, and professional services before becoming a senior digital transformation executive at ThoughtWorks. He sits on boards, invests in startups, and spends his time helping executives separate what AI can actually do from what it is merely hyped to do.
The arc they moved through
A warm, rapid-fire start. Pride, personality, and the one word in each guest's language that English can't touch.
Where they come from, and how it shaped the way they build, invest, and lead. Terroir over resume.
The real work. The honest business, the hard decisions, the bet they're actually making. Host as peer, not fan.
The jam session. Escalating questions, playful to profound, and one answer the guest can save "pa' la sobremesa."
The same closing question, every guest, forever: who held the door open for you, and whose name goes on the door you're holding open?

